Sure, I don't see why not. But Ben's already got Spider-Monkey, and Spider-Man's webs are mechanical, not organic, so I personally don't think there's a whole lot of point to it. And I prefer Ben's aliens to actually look alien to at least some extent, rather than just being humans with super-powers, ya know?
But yeah, I think all three of these series deserve to get continuations, and if I had the money, I'd pay the Ink Tank BIG BUCKS to do a 5YL series for each of them! I'd even hire extra artists and stuff to crank em out faster! But I'm not a multi-billionaire, unfortunately, and all the real billionaires would rather burn their money on shiney cars, or on carrying their presidential candidates to the oval-office for them, so sadly we may never get to see 5YL-quality continuations for any of them.
But I'm still gonna try and make a Sly Cooper fanfiction that finally answers the Cliffhanger at the end of Sly 4! Sly Cooper: 5 Years Later!