First of all, the omnitrix would have to be hacked and have its failsafe turned off in order to scan Mutated/Mutant DNA, so it can’t scan any quirked humans unless it was “broken”.

But, if the omnitrix were to be Hacked, then yes it could scan the DNA of anything as well as Nomus.

Um what is a high end Nomu?

High End Nomus are are artificial humans from My Hero Academy. Compared to regular nomus the High Ends can have up to 6 quirks and still possess the ability to think and act for themselves. This allows them to go up against high ranking heroes along with strategizing just how to beat them.

Since Nomu are surgicly enahced humans No.